It’s usually physically harmless, but it can lead to unwanted appearance changes
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Lavender oil
Conclusion: Spironolactone is known to cause bilateral gynecomastia; few reports are available on unilateral cases; It is important for the clinician to keep this fact in mind, take
Gynecomastia must be distinguished from the
Unlike eplerenone, spironolactone is known to
We suggest
, GnRH agonists and high-dose ketoconazole (600 mg/day or greater), were not included
For people with gynecomastia, having enlarged breasts can be stressful and embarrassing
Diagnosis of gynecomastia was identified by the International Classification for Diseases, 9th edition (ICD-9) and 10th edition (ICD-10) codes
A 52-year-old male patient receiving multiple antihypertensives including hydrochlorothiazide presented with muscle weakness and
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Past medical history should address disorders that can cause gynecomastia and include a history of all prescribed and over-the "Spironolactone, an aldosterone antagonist, can bind to androgen and progesterone receptors, in addition to the mineralocorticoid receptors, resulting in breast tenderness and gynecomastia
Using a nationwide prescription drug registry between 1995
5%) at 200 mg/day, and in 6 of 9 (66
These may be categorised into: exposure to partners using oestrogen containing vaginal creams; foods contaminated with oestrogens for example, from oestrogen or diethylstilboestrol injected cows
Spironolactone-induced gynecomastia is widely described in the literature [31], [32], and appears to be dose All neuroleptics are known to cause hyperprolactinemia by blocking the dopamine-mediated
Many drugs can cause gynecomastia as much as several active ingredients, which have been associated to this condition
The most common adverse effect was gynecomastia
Gynecomastia may develop in association with the use of spironolactone; physicians should be alert to its possible onset
Talk to your doctor if you have concerns about this
Both Digoxin and Furosemide are also reported to cause the same condition
stomach upset
[14, 15] Prolactin has also been reported to decrease androgen receptors and increase estrogen and progesterone receptors in breast cancer cells, which can lead to male gynecomastia