Amlodipine is broken down by enzymes (CYP3A4) in the lower intestine
Conclusion: An interaction between grapefruit juice and amlodipine was demonstrated
Prominent medications known to interact with grapefruit include statins, antiarrhythmic agents, immunosuppressive agents, and calcium channel blockers
Drug Interactions with Grapefruit Juice
Evidence-based interaction details between Amlodipine Besylate, Benazepril (brand name (s): Lotrel) and Grapefruit, including interaction severity and
Manufacturer advises avoid