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0 were excluded from the RCTs confirming superiority of PCC over FFP
Intracranial hemorrhage (ICH) is an inclusive term referring to several different conditions, including hemorrhagic stroke, subdural hematoma, and epidural
The high early mortality of approximately 50% has
After such an event, clinicians
Atrial fibrillation increases the risk of stroke 3- to 5-fold and is implicated in about 15% of all strokes every year
1-3 Prior studies suggest patients on either of
Methods: PubMed, EMBASE, Web of Science, and the Cochrane Library were searched for relevant randomized controlled
Warfarin-associated intracerebral hemorrhage (ICH) is the most feared complication of anticoagulation therapy 1 and is becoming more common with increased use of this medication in the aging population
5
have a significantly higher prevalence of immediate traumatic intracranial hemorrhage compared with patients receiving warfarin
Intracranial hemorrhage (ICH) is the most devastating bleeding event with mortality rates of 40% at 30 days and 65% at 90 days [2]
5 increase in PTR over the entire range, the risk for intracerebral hemorrhage doubled (odds ratio, 2
retrospectively evaluated the management of anticoagulation in 52 patients with mechanical heart valves and intracranial bleeding and found that warfarin was restarted in 28 patients by day 30 without the recurrence of intracranial hemorrhage [ 28 ]
Prothrombin complex concentrates (PCCs) are indicated for urgent reversal of anticoagulation after aaICH
Patients with mechanical heart valves are at high thrombotic risk and require warfarin
Intracranial hemorrhage is a life-threatening condition, the outcome of which can be improved by intensive care
Methods: Subjects were drawn from an ongoing prospective cohort study of ICH outcome
Objective To investigate the
A brain bleed (intracranial hemorrhage) is a type of stroke
66 with AF, in order to assess the risk of intracranial hemorrhage after warfarin and rivaroxaban use, and 33 observational studies involving 1 391 923 patients (646 118 used rivaroxaban and 745
6 (95% CI, 1