In addition, Lipitor can be used to reduce other heart-related Statins like Lipitor (atorvastatin) can interact with many different medications such as Paxlovid (nirmatrelvir) and the HIV medication Norvir (ritonavir)
Having too much cholesterol in the blood increases the risk of heart attacks and strokes
4, 2022 Drug interactions | Vitamin and supplement interactions | Food interactions | Other contraindications | Signs of an interaction Joint pain
These include: gemfibrozil (Lopid) and other fibrates (which help lower triglycerides levels) certain antifungals, antibiotics, and antiviral drugs; Find everything you need to know about Lipitor (atorvastatin), including what it is used for, warnings, reviews, side effects, and interactions
LIPITOR plasma levels can be significantly increased with concomitant administration of inhibitors of CYP3A4 and transporters
The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive
Although rare, the most serious of these is rhabdomyolysis
Alcohol (Ethanol) atorvastatin
Lipitor may interact with other medications
This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue
Lipitor
Atorvastatin competitively inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase
Also, avoid excess alcohol use, as this may cause serious liver problems
It does not apply if you are taking niacin at dosages commonly used in nutritional supplements
This can be harmful or prevent Statins are also more likely to cause muscle damage in people with an underactive thyroid
Applies to: amlodipine and Lipitor (atorvastatin) AmLODIPine may increase the blood levels of atorvastatin
Fibrates include fenofibrate (Tricor) and According to the AHA writing committee, the 2 most common pharmacokinetic drug-drug interactions that involve statins are those mediated by the cytochrome P-450 (CYP450) enzyme system and permeability glycoprotein
Decreased drug metabolism may lead to accumulation and increased risk of toxicity, including biochemical abnormalities of liver function and, rarely, jaundice, hepatitis, cirrhosis, fatty change in the liver, and fulminant hepatic necrosis
This can increase the risk of side effects such as liver damage and a rare but serious condition This can cause high levels of potassium in your blood
Theoretically, pomegranate might increase levels of drugs metabolized by CYP3A4, but most research suggests this interaction is unlikely to be clinically significant
3 million patients in the US received lipid-lowering drugs and PPIs, respectively 1
It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body
To avoid potential interactions, it is often recommended to "hold" or not take Lipitor during the entire duration of therapy with a strong CYP3A4 inhibitor
This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue
Grapefruit juice can increase the blood levels of atorvastatin
Some studies suggest that high doses of magnesium may interfere with the absorption of statins, reducing their effectiveness
In some cases, rhabdomyolysis can cause kidney damage and even death
This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue
1
Grapefruit juice inhibits a system of enzymes that helps break down dozens of medications, including Lipitor, Mevacor, and Zocor
Lipitor
A total of 495 drugs are known to interact with levofloxacin
Lipitor
Other antiviral medications
It can also interact with certain foods
Drug Interactions for Lipitor Drug Interactions That May Increase The Risk Of Myopathy And Rhabdomyolysis With LIPITOR
Tell each of your healthcare providers about all medicines you use
Always check for them on the drug
However, there are exceptions as well
Drug information provided by: Merative, Micromedex
You should avoid large quantities of grapefruit or grapefruit juice, which can increase the risk of
This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue
Applies to: Prilosec (omeprazole) and Lipitor (atorvastatin) Talk to your doctor before using atorvastatin together with omeprazole
Theoretically, pomegranate might increase levels of drugs metabolized by CYP3A4, but most research suggests this interaction is unlikely to be clinically significant
Combining these medications may significantly increase the blood levels of atorvastatin
There are 29 drugs known to interact with Metamucil (psyllium), along with 4 disease interactions, and 1 alcohol/food interaction
Joint pain
Lipitor is used to treat the following conditions: Kellick et al Statins and drug interactions S31
Atorvastatin oral tablet can interact with other medications, vitamins, or herbs you may be taking
atorvastatin clopidogrel
There are 250 drugs known to interact with semaglutide, along with 6 disease interactions, and 2 alcohol/food interactions
Major: Highly clinically significant
Using atorvastatin together with niacin may increase the risk of HMG-CoA reductase inhibitors (statins) are lipid-lowering medications used in the primary, secondary, and tertiary prevention of coronary heart disease
There are over 200 drugs known to cause interactions with Lipitor, whether in a very minor way or with such severe consequences that the risk of taking the drug with Lipitor outweighs any possible benefit taking the two of them together
Below, we review seven important metformin drug interactions to be aware of
Atorvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins)