However, “real-life” data on statin use in patients with chronic liver disease and its impact on overall and liver-related survival
10 However, this recommendation is based on post hoc analysis of the trial population, that excluded patients
This
The use of drinks that contain alcohol raises your risk for liver disease from atorvastatin
In an article for Northern Virginia Magazine, Sudip Saha, MD, wrote about the role of statins in treating high cholesterol
The diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the American Association for the Study of Liver Diseases
The
Regardless of The evolution of chronic liver injuries from benign and manageable dysfunction to life threatening end-stage liver disease with severe complications renders chronic liver disease a global health burden
There is no need to avoid statin therapy in patients with stable chronic liver disease or normal modestly elevated transaminases levels up to three times the upper limit of normal
95 per 100,000 person-days], but higher in those on high doses of atorvastatin [40 or 80 mg A year ago my Cholesterol was still high and I had changed doctors and was prescribed Atorvastatin 10mg after 2 months my doctor sent me for blood tests and in a phone call when I was at work he told me that Atorvastatin had caused Liver damage
It would stand to reason that patients
Liver disease that is attributable to statin use is rare, and it is uncertain whether raised serum ALT represents true hepatotoxicity
Food and Drug Administration (FDA) warned about the risk of liver damage in 2009 and again in 2012
NAFLD(nonalcoholic fatty liver disease) is a known risk factor for cardiovascular disease
Pathophysiology and Mechanism of Action
Liver injury has a broad definition, but generally includes, at minimum, highly elevated liver enzymes which are directly correlated with liver function and often a precursor to various liver diseases
For the best results, exercise and eat healthy while taking atorvastatin
Of 437 patients with moderately abnormal liver tests at baseline, which were possibly associated with non-alcoholic fatty liver disease, 227 who were treated with a statin (mainly atorvastatin 24 mg per day) had substantial improvement in liver tests (p<0·0001) whereas 210 not treated with a statin had further increases of liver enzyme
Thus, based on available evidence, statin therapy should not be Atorvastatin is not suitable for some people
Of 1188 patients with drug‐induced liver injury (DILI) evaluated by the DILI Network, just 22 (1
Do not prescribe statins to: People with active liver disease
Women who are pregnant or people who have active or chronic liver disease should not take statins