Check with your doctor immediately if any of the following side effects occur: More common
They can’t be seen, but they can be spotted by the symptoms: Unusual or prolonged bleeding Frequent bruising Skin discoloration, like spots or a rash Nosebleeds Unusual tiredness
Call your doctor at once if the person taking valproic acid has signs of liver or pancreas problems, such as: loss of appetite, upper stomach pain (that may spread to
These effects may include: Abdominal pain Diarrhea
Long-term use of valproic acid is related to metabolic disorders such as the increase of body weight and might be changes of lipid profiles which are contributed to
1%):
Our analysis depicts that there is a relationship between the long-term VA treatment and the level of total cholesterol (P=0
Valproic acid appears to be use cautionally in obese females with epil
Serious Depakote side effects include: Birth defects such as spina bifida
Suicidal thoughts and actions
The potentially debilitating side effects are reasons people typically end up withdrawing from this medication
This study aimed to review the influence of VPA therapy on serum lipid profiles in children with epilepsy
VPA has a well-studied side effect profile, including obesity, insulin resistance, metabolic disorder and severe forms of hepatotoxicity []
All were patients in a long-term care facility and ranged in age from 2 to 29 years (mean 14
These side effects may go away during treatment as your body adjusts to the medicine
Delayed release tablets: 125 mg, 250 mg, 500 mg
Valproic acid (VPA) has been reported to cause cognitive decline and parkinsonism that are reversed with cessation of medication
Myopathy associated Hippocampal synaptic plasticity, memory, and epilepsy: effects of long-term valproic acid treatment
The association between valproate and female reproductive disorders is well understood and delineated
Valproic acid (VA) is the antiepileptic, antimigraine and anti-mental disturbances agent
2008 Feb;9(2):285 Background Previous studies have reported that long-term use of valproic acid can cause changes in bone metabolism in children
Seek medical treatment if you have a serious drug reaction that can affect
Long-term use of valproic acid is related to metabolic disorders such as the increase of body weight and might be changes of lipid profiles which are contributed to cardiovascular events, however, these effects have not been fully determined
HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neurodegenerative disease of the central nervous system induced by human T-lymphotropic virus type 1
Background: Valproic acid (VPA) is a broad spectrum antiepileptic drug (AED) that is generally regarded as a first-choice agent for most forms of idiopathic and symptomatic generalised epilepsies
Seizure freedom rates for ethosuximide and valproic acid were 53% and 58%, respectively