Continue to use polymyxin B and talk to your doctor about any side effects An unusual or allergic reaction to polymyxin B, trimethoprim, other medications, foods, dyes, or preservatives; Pregnant or trying to get pregnant; Breast-feeding; How should I use this medication? This medication is used in the eye
IV: 15,000-25,000 units/kg/day divided q12hr; not to exceed 25,000 units/kg/day
polymyxin B and trimethoprim ophthalmic may cause serious side effects
Polytrim (polymyxin B / trimethoprim) is a combination antibiotic eye drop
Polymyxin B and trimethoprim combination is used to treat eye infections, including acute bacterial conjunctivitis and blepharoconjunctivitis
Drugs & Diseases trimethoprim/polymyxin B ophthalmic (Rx) Brand and Other Names: Polytrim Ophthalmic Solution Classes: Antibiotics, Ophthalmic Combos Dosing & Uses
difficulty seeing at night
It will not treat
More commonly, some burning, stinging, irritation, itching, redness
Mutagenesis: Trimethoprim was demonstrated to be non-mutagenic in the Ames assay
Rare side effects of Trimethoprim/Polymyxin B Ophthalmic include: none
[1] While it is useful for many Gram negative infections, it is not useful for Gram positive infections
Polymyxin B sulfate and trimethoprim ophthalmic solution, USP is a sterile antimicrobial solution for topical ophthalmic use
They were isolated from Paenibacillus polymyxa and became available for clinical use in the 1950s []
Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and
increased tearing
Polymyxin-B-trimethoprim ophthalmic solution has been assigned to pregnancy category C by the FDA
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Polymyxin B and trimethoprim combination is used to treat eye infections, including acute bacterial conjunctivitis and blepharoconjunctivitis
Sulfacetamide (Bleph-10) 10% sol 1-2gtt q2-3h x 7-10d, taper to twice daily with improvement
unsteadiness, trembling, or other problems with muscle control or coordination
This may occur on instillation, within 48 hours, or at any time with extended use
Mutagenesis: Trimethoprim was demonstrated to be non-mutagenic in the Ames assay
2 and osmolality of 270 to 310 mOsm/kg
It has pH of 4
1%-10,000 units/ml ophthalmic drops 1-2 drops 4 times daily Topical therapy is not necessary if patient is on concurrent systemic therapy with coverage against likely causative organisms Commonly caused by viruses, consider supportive treatment such as warm compresses or cold saline drops Polymyxin B Sulfate and Trimethoprim Ophthalmic Solution is a sterile antimicrobial solution for topical ophthalmic use