Small case reports have shown benefit with budesonide in CID secondary to 5-FU and irinotecan, but Feb 1, 2024 · However, elderly patients are more likely to have unwanted side effects (eg, stomach problems, severe diarrhea, nausea or vomiting, which may require caution and an adjustment in the dose for patients receiving capecitabine
Capecitabine has been reported to increase serum phenytoin levels and the international normalized ratio in patients receiving concomitant phenytoin and warfarin This topic will review the management of CRD
This guidance has been produced to support the following: Prevention and management of diarrhoea in adult patients receiving systemic anti-cancer treatment (SACT) including
Abstract Chemotherapy-induced diarrhoea (CID) is a risk of antineoplastic regimens, often associated with 5-fluorouracil (5-FU), irinotecan and capecitabine
Capecitabine is used to manage tumor
Development of the guidelines
The timing and severity of Xeloda’s side effects can vary from person to person
Under the terms of the agreement, Cheplapharm will receive product rights for Xeloda ® in certain countries worldwide including the USA
In patients undergoing treatment for metastatic breast cancer with capecitabine monotherapy, nausea and diarrhea were reported in more than half of patients (57% and 53%, respectively)
pain, redness, swelling, sores, or ulcers in your mouth or on your lips
These include heart attack, heart failure, cardiac arrest, and abnormal heart rhythm
difficulty with swallowing or pain in the back of throat or chest when swallowing
We present a case with terminal ileitis as a rare adverse event of capecitabine treatment
vomiting blood or material that looks like coffee grounds
Diarrhea is the dose-limiting and major toxicity of
Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes
The guide is also available in a condensed pocket guide format and 2-page algorithm
Common side effects include abdominal pain, vomiting, diarrhea, weakness, and rashes