With concomitant omeprazole treatment, the mean AUC0-24 and Cmax of itraconazole were significantly reduced by 64% and 66%, respectively
Several studies have shown that omeprazole carries a considerable potential for drug interactions because of its high affinity for CYP2C19 and moderate
SUBA-itraconazole and Sporanox are two oral formulations of itraconazole
Drug Interactions According to the U
Results: Omeprazole has actual adverse influences on the pharmacokinetics of medications such as diazepam, carbamazepine, clozapine, indinavir, nelfinavir, atazanavir, rilpivirine
Of the total drug interactions, 251 are major, 379 are moderate, and 25 are minor
This is a physicochemical interaction that is likely to occur in dogs and cats as it does in humans
Although rare, the most serious of these is
These classifications are only a guideline
Rabeprazole These classifications are only a guideline
Moderate Background: Omeprazole, a proton pump inhibitor (PPI), is widely used for the treatment of dyspepsia, peptic ulcer, gastroesophageal reflux disease, and functional dyspepsia
On the other hand, no
In addition, omeprazole (CYP2C19 substrate and inhibitor) use of the strong 3A4
It belongs to a class of drugs known as azole antifungals
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Itraconazole: Strong P-gp inhibition and moderate CYP3A4 inhibition 2: Consider alternative, decrease dose by 50% if unavoidable 2: Major: The role of cytochrome P2C19 in R-warfarin pharmacokinetics and its interaction with omeprazole
0b013e31816e2d8e Crossref Medline Google
There are 807 drugs known to interact with ketoconazole, along with 4 disease interactions, and 1 alcohol/food interaction
Sucralfate
12 days