(In fact, it's primarily used as a diuretic, so for its main use, it's actually its anti-androgen effects that are off-target)
It depends on how much T you produce and how your body reacts to spiro
You'll likely need a doctor's prescription for either as they're quite a bit harder to obtain than the more common anti-androgens
I understand that there's some discourse about Spironolactone actually having adverse effects in terms of desired feminization and breast growth
Feminizing hormone therapy often involves taking estrogen and anti-androgen hormones, such as estradiol or spironolactone
I use spironolactone as my androgen antagonist as a part of my feminizing hormone protocol
Its sole use in trans patients is to reduce the
As spironolactone may cause feminisation without inhibition of steroidogenesis, it is unclear which anti-androgen is more effective at feminisation
Although it is not generally considered a primary option in the management of
Recent estimates find that approximately 0
Additionally in the past it was used as chemical castration on gay men back when sodomy was Questions and discussions about, for, to, or from the Reddit transgender community
Rapid rises in demand for transgender health services have been observed worldwide (1, 2)
It's also a mild progestogen
Those changes are called secondary sex characteristics
Spironolactone is not poison
Thinning/slowed growth of facial / body hair
You will get growth (and pain), but not much real development
I'm on 100 mg spiro and 6mg estradiol (4mg in morning and 2mg at night) and will likely get them increased at some point
S we use primarily Spironolactone as an anti-androgen, but in Europe they seem to regularly prescribe Cyproterone Acetate
[deleted] • 3 yr
The effects spironolactone has on the skin and hormones were only found in later aftermarket studies of the drug
You can consider other alternatives to Spiro
Open to anyone with a question
4 Spironolactone is a moderate androgen receptor antagonist, 8, 9 which also partially inhibits 17α-hydroxylase/17,20 lyase, enzymes