The first-line treatment is trimethoprim-sulfamethoxazole, which has been the recommended empiric single agent against
FDA-approved in 1992, minocycline acts through protein synthesis inhibition
2016 Dec;71 (12):3620
Tetracyclines such as tigecycline, minocycline, and doxycycline are also effective agents and consistently display good activity against S
Stenotrophomonas maltophilia has emerged as an important opportunistic pathogen, causing infections whose management is often problematic due to its inherent
Clinical challenges treating Stenotrophomonas maltophilia infections: an update
A systematic review of the available evidence was conducted to evaluate the best treatment of SM infections to date, focusing on trimethoprim/sulfamethoxazole
S maltophilia, is usually resistant to aminoglycosides, antipseudomonal penicillins, and cephalosporins
maltophilia; however, there is limited published information on their effectiveness
Previously referred to as Pseudomonas maltophilia
Current interpretive susceptibility breakpoints of minocycline for Stenotrophomonas are a minimum inhibitory concentration (MIC) 4
1–3 S
However, no pharmacodynamic data are available to guide dosing or justify this breakpoint
6%, P = 0
Prevalence and treatment of Stenotrophomonas maltophilia among adult patients in United States hospitals
This retrospective study examined the antimicrobial susceptibility profile of clinical S
It can cause life-threatening opportunistic pneumonia, particularly among hospitalized patients
5%, the highest of the four antimicrobials tested with CLSI breakpoints ( Table 2 )
Although minocycline was first introduced in 1967
T Purpose of review: Stenotrophomonas maltophilia is an emerged opportunistic pathogen
Evaluation of the efficacy and safety outcomes of nonurinary, monomicrobial infections due to S
Current interpretive susceptibility breakpoints of minocycline for Stenotrophomonas are a minimum inhibitory concentration (MIC) 4
Stenotrophomonas maltophilia is a non-fermentative Gram-negative bacillus that can be transmitted by nosocomial sources including contaminated disinfectants, In the case of sulfonamide allergy, desensitization may be pursued
Background:Stenotrophomonas maltophilia is a multidrug-resistant organism with limited antibiotic treatment options