Define furosemide in mice

Studies on the induction by furosemide of chromosomal aberrations in mice were inconclusive. 21 mmol/kg) was shown to cause toxicity in mice, but not rats, at 24 h, without resulting in glutathione depletion

2024-03-29
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  1. 98 nmol equivalent bound/mg protein) than rat (0
  2. 1124/jpet
  3. dose of 80 mg based on BSA and oral bioavailability corrections)
  4. 3% Na and 0
  5. Previous evidence suggested hepatotoxicity