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All grantees regarding a maximum “number of doses” for extended-release Naltrexone (Section B, Question 3)
Medscape - Indication-specific dosing for ReVia, Vivitrol, Depade (naltrexone), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information
For narcotic addiction: Adults—At first, 25 milligrams (mg) (one-half tablet) for the first dose, then another 25 mg 1 hour later
For treatment of alcohol addiction, naltrexone is usually given in dosages of 50 milligrams per day although sometimes a patient
A 2004 RCT examined the effectiveness of naltrexone or acamprosate, alone or in combination, in preventing relapse in newly detoxified adults (N = 160)
Naltrexone is FDA-approved to treat the following conditions in adults: opioid use disorder (also called opioid dependence*); alcohol use disorder (also called alcohol dependence or alcoholism Naltrexone is usually given to block the effects of opioids or alcohol in people with addiction problems
In 2018, the prevalence of past-30-day binge drinking was 17% among
However, the article states that naltrexone is contraindicated in acute
Proper Use
Each extended-release tablet contains naltrexone 8 mg/bupropion 90 mg:Initial dose: Week 1: One tablet orally once a day in the morning
Alcohol misuse is the fifth leading risk factor for premature death and disability worldwide
Naltrexone may reduce alcohol craving that alcohol-dependent people often feel
extended release tablet
Dosing information
, day 2: 600 mg; day 3: 900 mg), titrating to final dosing regimen