Allopurinol type of inhibitor

An example is the inhibitor of polyamine biosynthesis, α-difluoromethylornithine (DFMO), which is an analogue of the amino acid ornithine , and is used to treat African trypanosomiasis (sleeping At low concentrations, allopurinol is a substrate for and competitive inhibitor of the enzyme; at higher concentrations, it is a noncompetitive inhibitor. Allopurinol, an analog of hypoxanthine, is widely used as an antigout drug, as xanthine oxidoreductase-mediated metabolism of allopurinol to oxypurinol leads to oxypurinol rotation in the enzyme active site and reduction of the molybdenum Mo Allopurinol -- a competitive inhibitor of xanthine oxidase -- could alleviate the combined effects of fructose feeding and copper deficiency

2024-03-28
    Diarrhea after keflex
  1. FROM THE STUDY SET
  2. Investigational
  3. Allopurinol is the first-line urate-lowering therapy
  4. 350 (0