Child: ≥1 year Same as adult dose
Pregnancy Category C: Ofloxacin has been shown to have an embryocidal effect in rats and in rabbits when given in doses of 810 mg/kg/day (equivalent to 9000 times the maximum recommended daily ophthalmic dose) and 160 mg/kg/day (equivalent to 1800 times the maximum recommended daily ophthalmic dose)
Pregnancy Category C
Pregnancy Category C Ofloxacin has not been shown to have any teratogenic effects at oral doses as high as 810 mg/kg/day (11 times the recommended maximum human dose based on mg/m 2 or 50 times based on mg/kg) and 160 mg/kg/day (4 times the recommended maximum human dose based on mg/m 2 or 10 times based on mg/kg)
Most fluoroquinolones are metabolized in the liver and excreted in urine, reaching high levels in urine
Animal studies have failed to reveal evidence of teratogenicity at oral doses up to 500 mg/kg/day in rats
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Levofloxacin is the S-enantiomer of the fluoroquinolone, ofloxacin
Before using this medication, inform your doctor if you are/have: This drug is a pregnancy category C drug
Comments:-If this drug is used during pregnancy, the patient should be apprised of the potential harm to the fetus