Pemphigus pathogenesis is related to IgG autoantibodies targeting various adhesion molecules in the epidermis, including desmoglein (Dsg) 1 and 3, major
Pemphigus vulgaris (PV) is a potentially fatal autoimmune, intraepithelial disease characterized by flaccid blisters and erosions of the skin and mucous
1 A new formulation of cyclosporine, Neoral, uses an ultramicronized form of the drug
Use of modified ciclosporin in the management of feline
Pemphigus foliaceus (PF) is one of the most common canine cutaneous autoimmune diseases associated with a production of pathogenic autoantibodies that
Since the initial report of the immunosuppressive action of the fungal peptide
The two main types of pemphigus are pemphigus vulgaris (PV) and pemphigus foliaceus (PF)
We wished to avoid glucocorticoids and, therefore, prescribed oral
Efficacy of cyclosporine for treatment induction of canine pemphigus foliaceus
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Pemphigus foliaceus is a relatively common canine autoimmune skin disease characterized by scaling, crusts, pustules, alopecia, and erosions, which may remain localized or become generalized
Pemphigus foliaceus (PF) is the most common of these, wherein autoantibodies are responsible for destroying the proteins that bind epidermal cells together
Pemphigus foliaceus (PF): The term means "leaf-like pemphigus”
Contact D
Systemic immunosuppressive therapy with cyclosporine and azathioprine was effective, and the dog survived for >2 years from the initial presentation
compared oral CS monotherapy with a combined therapy of oral CYP and CS as well as a combined therapy of cyclosporine and CS
No difference in efficacy between these treatments were observed, but adverse events were higher in
Immunosuppressive therapy, including glucocorticoids, cyclosporine, and chlorambucil, is commonly used to treat the disorder, and typically remission is observed with treatment
Clinical outcomes and
However, in contrast to pemphigus vulgaris (PV) where mucosal lesions are classically present, pemphigus
This study is a retrospective review of medical records from 2015 to 2020 to evaluate the therapeutic outcomes of 11 PF dogs treated with oral modifie
Pemphigus foliaceus is the most common autoimmune skin disease in dogs