Levofloxacin inhibits the DNA gyrase and topoisomerase IV
Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of Dec 17, 2019 · To this end 19 F NMR, which is a proven technique for the quality and quantity assessment of pharmaceutical products, was employed
J Pharm Pharmacol
143799 Da ChemSpider ID 131410 - 1 of 1 defined stereocentres More details: Names Properties Searches Spectra
General tips for obtaining a higher concentration: Please warm the tube at 37 ℃ for 10 minutes and/or shake it in the ultrasonic bath for a while
It is distributed into body tissues, especially in the skin and lung tissues
A notable improvement in the solubility of LEV was observed (104 mg/ml) with an almost threefold increase in the solubility when compared with the reported
DMSO : 18 mg/mL ( (49
Levofloxacin is a fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary
Levofloxacin is considered soluble to freely soluble in this pH range, as defined by USP nomenclature
It varies from x 2 = 4
99% was obtained from Merck
Sulfonate Insoluble - Di-isobutylene (0
very soluble in DMSO, concentrated ammonia, 10% NaOH with formation of a black precipitate (Ag 2 O); slightly soluble in DMF and 10% HCl, insoluble in water Table 3: Solubility of triclosan in selected solvents and chemicals; Solvent Solubility at 25°C (g Triclosan/100 g solvent) Distilled water (20°C) 0
30: Triethanolamine >100: Acetone >100: Ethanol 70% or 95% >100: Isopropanol Levofloxacin(100986-85-4) Reference standards for Pharmacological research
The data demonstrate that from pH 0
Moreover, they may have low
8, the solubility of levofloxacin is essentially constant (approximately 100 mg/mL)
8, the solubility increases rapidly to its maximum at pH 6
It varies from x 2 = 4
The solubility of levofloxacin in six solvents including ethanol, 1-propanol, 2-propanol, 1-butanol, acetic acid and ethyl acetate in the temperature range of 288
The present study reports on the electrospinning behavior of PVA solutions in DMSO–water binary mixtures at a temperature of 35 °C
8, the solubility of levofloxacin is essentially constant (approximately 100 mg/mL)
The solubility of theophylline in water is 5
To determine the steady-state plasma, epithelial lining fluid (ELF), and alveolar macrophage (AM) concentrations of levofloxacin and ciprofloxacin
0 (cal / cm3)1/2: Hildebrand’s: DMSO is highly stable at temperatures below 150°C
In order to save you time, TOKU-E Company has compiled a comprehensive list of frequently used antimicrobial, plant biology, and anticancer compounds along with Levofloxacin (Oral Route) Drug information provided by: Merative, Micromedex
The “mole fraction solubilities (x e)” of BNB in DMSO and water mixtures were determined at “T = 298