It’s available as a generic drug and as the brand-name drugs Trileptal and
It works by decreasing nerve impulses that cause seizures and pain
For instance, the seizure medications carbamazepine and oxcarbazepine can increase sensitivity to ADH
Oxcarbazepine oral suspension is indicated for: Adults: Monotherapy or adjunctive therapy in the treatment of partial-onset seizures
Oxcarbazepine is an anticonvulsant drug that reduces the incidence of seizures in epilepsy by inhibiting abnormal electrical activity in the brain
Absorption and Distribution
Oxcarbazepine (OXC) is an antiepileptic drug developed as a keto derivative of carbamazepine (CBZ) and is widely used as a mood stabilizer in patients with bipolar
We present a case of a 60-year-old female patient presenting in emergency department with history of carbamazepine-induced hyponatremia
Cases of symptomatic hyponatremia and syndrome of inappropriate antidiuretic hormone secretion (SIADH) have been reported during post-marketing use
Oxcarbazepine (OXC) is an antiepileptic drug developed as a keto derivative of carbamazepine (CBZ) may be the result of a direct effect on the renal tubules or enhancement of their responsiveness to circulating antidiuretic hormone
Most patients with OXC-induced hyponatremia are asymptomatic, so the presence of severe or symptomatic hyponatremia, which requires electrolyte correction or discontinuation of OXC therapy, has more important clinically
Daily doses above 1200 mg/day show somewhat greater effectiveness in General
Extended-release: Initial dose: 600 mg orally once a day for one week, increased by increments of 600 mg per day at weekly intervals as clinically indicated
1 whose observations and diagnostic criteria remain essentially unchanged 1, 2, 3, 4
It is widely used as a mood stabilizer in Syndrome of Inappropriate Antidiuretic Hormone Abstract and Figures
It is a structural analog of carbamazepine; however, it follows a different metabolic pathway in which it is converted to a different active metabolite
This is not a complete list of side effects and others may occur
Oxcarbazepine is 10,11-Dihydro-10-oxo-5 H -dibenz [b, f ]azepine-5-carboxamide, and its structural formula is: Oxcarbazepine is a white to faintly orange crystalline powder
This carbamazepine antidiuretic effect is not well characterized, and frequently, it has been suggested to be responsible for the stimulation of the vasopressin release from the pituitary gland (syndrome of inappropriate antidiuretic hormone secretion, SIADH)
Along with its needed effects, a medicine may cause some unwanted effects
swelling of the face, ankles, or hands
As a result, more water is retained in the body, which dilutes the level of sodium in the body