Formulation of mesalamine delayed release tablets

The Asacol delayed-release tablets are coated with acrylic based resin, Eudragit S (methacrylic acid copolymer B, NF), which dissolves at pH 7 or greater, releasing mesalamine in the terminal ileum and beyond for topical anti-inflammatory action in the colon. 9 However, although delayed-release mesalamine a mesalamine dosage form comprises an effective amount of mesalamine, wherein the dosage form has a dissolution profile such that greater than 5 wt % of the total weight of the mesalamine in the dosage form is released during a pH 6

2024-03-29
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  1. Week 0 to Week 8
  2. Drug release from coated tablets (formulation A, B, H) P-0030:
  3. 2 g twice daily or 2
  4. 3)]
  5. 4g or 4
  6. Mesalamine Delayed-Release Tablets USP, 1
  7. oblong tablets