Adverse reactions reported in mebendazole-treated subjects from the 39 clinical trials are shown in Table 1 below
Histologic analysis of kidney and liver showed no evidence of toxicity (Fig
Treatment with albendazole or mebendazole is indicated for visceral toxocariasis, although optimal duration of treatment is undefined
It is of particular note that albendazole and mebendazole have been repositioned as promising anti-cancer drugs
A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas Phase I: determine if MBZ is tolerated when used in combination with the current three-drug regimen
Key Features
Benzimidazole induces concurrent apoptosis and pyroptosis of human glioblastoma cells as well as inhibits cell cycle via p53-p21 pathway , while mebendazole was associated with p53-independent induction of p21 and tubule depolymerization in ovarian cancer
8 years
Antiparasitic drugs such as fenbendazole have caught the attention of researchers studying pancreatic cancer
purple or red skin rash with blisters of skin and mouth; fevers, and weakness
Vermox
However, evidence supporting the four current treatment modalities is inadequate, and treatment options remain controversial
Mebendazole attenuated ulcerative colitis-associated clinical symptoms in the mouse model
We became interested in fenbendazole when our university veterinarians recommended that all experimental