Antidepressants
Membrane stabilizers: Medications such as gabapentin can be used to reduce the pain associated with PHN
In terms of treatment, guidelines recommend patients use tricyclic antidepressants (TCAs), gabapentin, pregabalin, and 5% lidocaine patches as the first
PHN is likely to interfere with sleep and daily
Like the antidepressants used for post-herpetic neuralgia, they should be
Objectives: Summarize the different indications for gabapentin
Serious symptoms of shingles include chronic pain, vision changes, and altered blood flow to the brain
PHN is long-term nerve pain
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The third gabapentin formulation for PHN treatment is another extended-release product, Horizant
Gabapentin capsules are given orally with or without food
Gabapentin enacarbil (brand name Horizant), a prodrug of gabapentin that can be taken once daily, may be used in the treatment of RLS and postherpetic neuralgia
Objective To systematically evaluate the clinical efficacy of pregabalin and gabapentin in the treatment of postherpetic neuralgia (PHN), including the difference in pain control and occurrence of adverse reactions
41, 42 A therapeutic dosage for pregabalin (150–600 mg/day, taken in two or three doses per day) is lower than for gabapentin, and a 1-week titration is recommended to reach the effective dosage
These advances are the demonstrations that gabapentin, the lidocaine patch 5%, and opioid analgesics are efficacious in patients with PHN, and the report that nortriptyline and
This description applies to a highly heterogeneous spectrum of pain syndromes presenting with a broad range of signs and symptoms, with various
Because of its severity and chronicity, PHN is a considerable health-care problem
Pregabalin is the newest agent to gain approval There is evidence to support the use of tricyclic antidepressants (off-label use) and the antiepileptic drugs gabapentin and pregabalin (Food and Drug Administration–approved) for the treatment Some patients may continue to experience pain for months to years after the resolution of the rash, a condition known as postherpetic neuralgia (PHN)
1 Vigilance and early treatment of the acute infection can result in a reduced incidence of the chronic symptoms of PHN
Capsaicin and valproic acid are considered third-line therapies
Postherpetic neuralgia (PHN) is a chronic and painful condition that may occur after a herpes zoster infection
Efficacy and tolerability of gastric-retentive gabapentin for the treatment of postherpetic neuralgia: Results of a double-blind, randomized, placebo-controlled clinical trial