Hydroxychloroquine Retinopathy
Anterior Chamber: deep and quiet
Several adverse effects associated with CQ and HCQ have been reported including gastrointestinal discomfort, allergic reactions, cardiomyopathy, cardiac conduction defects, neuromyotoxicity
This type of disease happens when the body's immune
Hydroxychloroquine-related eye problems were once considered rare, but better detection methods now show they occur in a greater proportion of patients — more than the 7% originally thought
3 +/- 2
It also
Most of these side effects are reversible if treatment is stopped promptly
15-17,36 The risk of toxicity is increased with higher doses and a longer duration of treatment
headache
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, and sex organs
Plaquenil (hydroxychloroquine) is a medicine commonly used to treat patients with systemic lupus erythematosus and rheumatoid arthritis
Some people who take Plaquenil have a higher risk of retinal damage than others
people over 60 years old
107, 108 Hydroxychloroquine has been associated Patients classified as having stable retinal thickness showed a normal distribution of thinning rates by a Shapiro–Wilk test and an average thinning rate of 0
“Retinal toxicity from hydroxychloroquine use cannot be completely prevented, but effective screening should recognize retinal toxicity A rare side effect of Plaquenil is damage to the eye's retina
When retinopathy is not recognized until a bull's-eye appears, the disease can progress for years, often with foveal thinning and an eventual loss of visual acuity
When calculating the dose of hydroxychloroquine, the recommended dose of ≤ 5 mg/kg actual body weight significantly reduces the overall risk of disease