This information should not take the place of medical care and advice from your healthcare providers
What is meclizine? Meclizine is a medication that has been used to treat nausea and vomiting, motion sickness, and vertigo […] Meclizine is a medication used to manage and treat nausea, vomiting, and dizziness caused by motion sickness and vertigo
Alternatively, discontinue doxylamine if it was completely ineffective
Some brand names that can include meclizine are AntivertÒ, BonineÒ Meclizine is used in adults and children aged 12 years and older to treat or prevent nausea, vomiting and dizziness caused by motion sickness
That means two things: Meclizine hydrochloride tablet
25 Although meclizine was previously thought to be teratogenic, studies have demonstrated its safety during pregnancy
1 Pregnancy
Antivert is also used to treat symptoms of vertigo (dizziness or spinning sensation) caused by disease that affects your inner ear
Consult your doctor before breastfeeding
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However, in a published study, an increased incidence of fetal malformations was observed 8
Bottom Line
During pregnancy, this medication Meclizine Hydrochloride Tablets USP, 25 mg are supplied as light yellow colored, oval shaped tablets with "AN 442" debossed on one side and plain on the other side
These effects occurred at doses as low as 25 mg/kg, which is approximately 2 times the maximum recommended human dose (100 mg) on a body surface area (mg/m 2 ) basis
Meclizine HCl, USP an oral antiemetic, is a white or slightly yellowish, crystalline powder
Risk Summary Data from epidemiological studies have not generally indicated a drug-associated risk of major birth defects with meclizine during pregnancy
1 Pregnancy
Risk Summary Data from epidemiological studies have not generally indicated a drug-associated risk of major birth defects with meclizine during pregnancy
However, in a published study, an increased incidence of fetal malformations was observed following oral administration of meclizine to pregnant rats during the period of organogenesis, at doses similar to those used clinically
Patients should avoid alcoholic beverages while taking meclizine hydrochloride [see Drug Interactions (7
PRECAUTIONS
These effects occurred at doses as low as 25 mg/kg, which is approximately 2 times the maximum recommended human dose (100 mg) on a body surface area (mg/m 2 ) basis
PRECAUTIONS
Risk Summary Data from epidemiological studies have not generally indicated a drug-associated risk of major birth defects with meclizine during pregnancy
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However, in a published study, an increased incidence of fetal malformations was observed following oral administration of meclizine to pregnant rats during the period of organogenesis, at doses similar to those used clinically
In a published study, oral administration of meclizine (25 mg/kg to 250 mg/kg) to pregnant rats during the period of organogenesis resulted in a high incidence of fetal malformations
Meclizine hydrochloride is an antihistamine that shows marked protective activity against nebulized histamine and lethal doses of intravenously injected histamine in guinea pigs
Some brand names for meclizine have included: Antivert, Bonine, and Meclicot
NCI Thesaurus (NCIt) A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness
Risk Summary Data from epidemiological studies have not generally indicated a drug-associated risk of major birth defects with meclizine during pregnancy
However, in a published study, an increased incidence of fetal malformations was 83008-022-30
Safety
Use in pregnancy: Meclizine is pregnancy Category B drug
Risk Summary Data from epidemiological studies have not generally indicated a drug-associated risk of major birth defects with meclizine during pregnancy
Drug Label Info
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US FDA pregnancy category B: Animal reproduction studies have failed to
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Nausea and vomiting of pregnancy is generally a mild, self-limited condition that may be
In a published study, oral administration of meclizine (25250
Meclizine Hydrochloride During Pregnancy and Breastfeeding Tell your doctor if you are pregnant before taking meclizine hydrochloride
8
However, in a published study, an increased incidence of fetal malformations was observed following oral administration of meclizine to pregnant rats during the
Patients should avoid alcoholic beverages while taking meclizine hydrochloride [see Drug Interactions (7
As with any medication, it is crucial to understand the risks and benefits associated with its use during pregnancy
However, in a published study, an increased incidence of fetal malformations was observed following oral administration of meclizine to pregnant rats during the period of
Serious side effects may include allergic reactions
However, in a published study, an increased incidence of fetal malformations was observed following oral administration of meclizine to pregnant rats during the period of
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The effectiveness of meclizine for these uses The current phase 1b clinical trial with a 14-day-repeated dose of meclizine was well tolerated and exhibited acceptable PK profiles in children with ACH aged 5–10 years in both cohorts administrated meclizine 12
Nursing Mothers It is not known whether this drug is excreted in human milk
For the treatment of vertigo, meclizine can be taken up to three times per day
However, in a published study, an increased incidence of fetal malformations was observed 8
do not indicate that medicine increases the risk of abnormalities when administered during pregnancy
Antivert is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness
The site and mechanism (meclizine hydrochloride) by women who are pregnant or may become (p<0
However, in a published study, an increased incidence of fetal malformations was observed following oral administration of meclizine to pregnant rats during the
For pregnant women: Meclizine is a category B pregnancy drug
Meclizine HCl is an antihistamine that shows marked protective activity against nebulized histamine and lethal doses of intravenously injected histamine in guinea pigs