5 nanograms/mL in the absence of hypokalaemia indicate that digoxin toxicity is unlikely
0 µg/L if the sample was collected at least 6 hours after the last dose
5-2 ng/mL
Use lower end of dosing (0
Patients with hypokalemia are more likely to develop digitalis toxicity and severe arrhythmias
Using Medicare Part D data from 2013 to 2019, total digoxin prescriptions (4
[ 3] Next: Interpretation
At first, the dose is usually 30 to 45 micrograms (mcg) per kilogram (kg) of body weight
1 ± 0
NARROW THERAPEUTIC INDEX:
Digoxin has been used for more than 50 years in patients with Atrial Fibrillation (AF), with the goal of Controlling Heart Rate (HR) and restoring sinus rhythm
0 ng/mL (1
2012 Jun 15;109 (12):1818-21
Therapeutic ranges have not been established for patients who are less than 16 years of age
mL-1 in adults and 0
Normal Results
5-0
Clinical studies have solidified the utility of digoxin in patients with left ventricular dysfunction and normal sinus rhythm
125 mg would be more appropriate
The reference range for digoxin is as follows: When no loading dose has been given this may take 7 days in patients with normal renal function and 14 days for elderly patients
5 - 2
8 to 2 ng/mL; Digoxin toxicity level: more than 2 ng/mL)
Patients with hypokalemia are more likely to develop digitalis toxicity and severe arrhythmias
Digoxin belongs to the class of medicines called digitalis
9 ng/mL for digoxin
0 ng/mL in adults are strongly suggestive of Thus, the therapeutic range of digoxin concentration currently recommended for the treatment of heart failure is 0
Digoxin: Time to steady state: 7–10 days
It is used to treat certain heart problems, although much less often than in the
9, and risk for toxicity if levels are > 2
1 Post hoc analysis of this trial found that mortality and hospitalisations were reduced if the serum digoxin was 0
0 ng/mL or greater as being within the normal range
In addition, this reference range was used before publication of the Digitalis Investigators Group trial
Toxicity may occur with plasma digoxin levels within therapeutic range, especially in chronic overdose
0 µg/L
, initial) dose; additional 25% fractions are administered every 6–8 hours
25 mg/day for maintenance [4,24] and plasma concentrations of 1-2ug/L are considered to be the limits of the therapeutic range [4, 23] but this has been revised recently to 0
If you’re being treated for a heart serum digoxin levels in 10 nontoxic patients (without atrial fibrillation) on oral doses of 0
6) and 1