Tacrolimus may be more advantageous since it lowers the likelihood of acute
Cyclosporine is an exciting new agent that has been heralded as a major advance in chemical immunosuppression for organ transplantation
Cyclosporin A (CyA) is a powerful immunosuppressive agent whose lack of myelotoxicity makes it unique among nonsteroidal drugs currently given for
Subjects: Clinical Trials
Immunosuppressive Drugs
Prednisone: Prednisone (or prednisolone) is a mainstay of treatment for most immune-mediated diseases
J Heart Lung Transplant Off Publ Int Soc Heart Transplant
Immunosuppressive therapy is required by transplant patients to prevent graft‐vs‐host disease and graft rejection
) Sometimes side effects from these medications are a result of an elevated blood level
The late 1970s and early 1980s brought revolutionary changes in drug development and discovery; two key developments were the technology to develop monoclonal antibodies (mAbs) for human therapeutic use and the discovery of the immunosuppressive effects of cyclosporin A from fermentation extracts of the fungal
This systematic review aims to summarize the current international clinical guidelines to highlight Immunosuppressive therapy is required by transplant patients to prevent graft-vs-host disease and graft rejection
Immunosuppressants or immune suppressants are usually used in conjunction with corticosteroids to block inflammatory reaction and decrease initial damage to cells in cases of organ transplantation and autoimmune diseases
Cyclosporin-A (CsA) is a fungus-derived molecule (Tolypocladium inflatum), discovered in 1970 by Borel and Stahelin in an attempt to develop a new antifungal treatment (2, 3)
Examples include cyclosporine and tacrolimus are calcineurin inhibitors
Thymectomy might be useful Application of the widely used immunosuppressant (ISS) cyclosporine (CsA) is severely limited by a number of serious side-effects such as kidney and neurotoxicity
The need for immunosuppressive drugs depends on the cause of the inflammation
Immunosuppressive drugs, also known as immunosuppressive agents, immunosuppressants and antirejection medications, are drugs that inhibit or prevent the activity of the immune system
Cyclosporin is the most frequently prescribed immunosuppressive drug after an organ transplant, and the incidence of gingival overgrowth has been found in nearly 53% of patients taking cyclosporin after renal transplants