Minocycline hydrochloride is a semisynthetic tetracycline derivative used widely for the treatment of acne vulgaris
Minocycline black bone disease is a rare finding that can cause concern when unexpectedly encountered during routine arthroplasty
Currently, no reports exist of
In the current orthopaedic literature, there have been no reports of minocycline-induced black bone disease of the glenohumeral joint
While the appearance is grossly abnormal in black bone disease, there has been
A case is presented in which long-term minocycline therapy (500g taken orally over 11 years) resulted in dark bone pigmentation (black bone disease) severe
The originality of this case is Oral presentation of minocycline-induced black bone disease
While the appearance is grossly abnormal in black bone disease, there has been no evidence suggesting that tissue "Minocycline black bone disease is a rare finding that can cause concern when unexpectedly encountered," the team wrote in their case study
a case study of minocycline-induced bone pigmentation
Black bone disease, caused by minocycline-induced hyperpigmentation, is rare
Long-term treatment An unusual black color of the skull was observed at incision of the coronal approach
Minocycline is widely used as a first-line agent for papulopustular acne, and has previously been reported as causing stains on teeth that are still forming
Canine studies demonstrate discolored thyroid tissue [ 25 , 26 ]
Although not all of these side effects may occur, if they do occur they may need medical attention
@article{Odell1995OralPO, title={Oral presentation of minocycline-induced black bone disease
We report the case of a patient who underwent surgery for bilateral hallux valgus and was found to have black discolouration of both first rays
Minocycline-induced hyperpigmentation is a well recognised phenomenon in skin, nail beds, thyroid, sclera, bones, and teeth
Its structural formula is: Each minocycline hydrochloride capsule, USP for oral administration, contains the equivalent of 50 mg, 75 mg or 100 mg of minocycline
1 These small modifications increase both the lipophilicity (increased lipid solubility) and the half-life of minocycline
Each Minocycline Hydrochloride Capsule, USP for oral administration, contains the equivalent of 50 mg, 75 mg, or 100 mg of minocycline