Of the total drug interactions, 399 are
See also Side Effects section
M14 (Ketoconazole) M7 (Ketoconazole) M8 (Ketoconazole) M9 (Ketoconazole) Only 2-4% of the ketoconazole dose is eliminated unchanged in the urine
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Two studies were conduced to assess the effects of ketoconazole, a CYP3A4/5 inhibitor; fluconazole, a CYP2C9 inhibitor; and paroxetine, a CYP2D6
Jan 25, 2024 · The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 113,196 people who take Ketoconazole and Fluconazole, and is updated regularly
As a consequence, fluconazole causes an increase in abnormal intracellular sterols, inhibiting the fungal cell’s ability to replicate
8 +/- 3
Jul 16, 2019 · In the presence of ketoconazole, modest increases in elvitegravir exposures were observed: 17% ↑ Cmax, 48% ↑ AUC, 67% ↑Cmin
It should be applied to the affected area once or twice a day and continued for a few days after all skin lesions are healed
You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications
Monitor for potential adverse effects such as nausea, irregular uterine bleeding, breast tenderness and headache
fluconazole, ketoconazole, Diflucan, itraconazole Mar 8, 2016 · Introduction
Antipyrine clearance is not altered at low doses (50 mg) of fluconazole; however, drug interactions with the use of larger doses can be anticipated with agents such as cyclosporin, phenytoin, oral hypoglycemics warfarin
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling)
A quantification method for the detection of pyrotinib M1 and IS in RLMs was successfully established with no other interfering peaks, as shown in Figure 2
A 60-year-old man with advanced gastric cancer achieved good pain control on a stable dose of methadone for 10 days
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Possibly a similar effect may occur with concomitant fluconazole and rifampin
200 mg
The findings are consistent with in vitro studies of differentially impaired zolpidem metabolism by azole derivatives
Apr 5, 2023 · In a drug-drug interaction study conducted in 12 patients to evaluate the effect of ketoconazole on the pharmacokinetics of bortezomib, a mean bortezomib AUC increase of 35% was observed
To report the influence of rifampin coadministration on the pharmacokinetics of fluconazole in 2 critically ill patients
They are reserved for extensive or severe infection for which topical antifungal agents are inappropriate or ineffective, because of high cost, potential side effects and drug interactions