2-4 Other drugs that may be used as initial
See full list on uptodate. 25 to 20 mg daily: $10 to $90: Thiazolidinediones: Pioglitazone (Actos) 15 to
Older adults with diabetes are at higher risk for both acute and chronic microvascular and macrovascular complications from the disease, including major lower-extremity amputations, myocardial infarctions, visual impairments, and end-stage renal disease, compared to any other age-group ( 3 )
They include medications like glipizide, glimepiride, and glyburide
The American Geriatrics Society’s Beers Criteria lists a strong recommendation based on high quality evidence that glyburide be avoided in the elderly due to the potential risks
Therefore, glyburide is not recommended for patients with a creatinine clearance less than 50 mL/min
Glipizide is the preferred agent if a sulfonylurea is to be used
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of glimepiride in the elderly