In the blood, it changes to diethyldithiocarbamic acid (DDC), which is degraded to form
Disulfiram - Uses, Side Effects, and More Common Brand(S): Antabuse Generic Name(S): disulfiram Antabuse (disulfiram) is an alcohol antagonist drug used to treat chronic alcoholism
Disulfiram At a Glance
Disulfiram, commonly sold under the brand name Antabuse, is a medication used in the treatment of alcohol use disorder and dependency
Regarded as one of the hallmarks of tumorigenesis and tumor progression, the evasion of apoptotic cell death would also account for treatment resistance or failure
, cognitive-behavioral therapy), incentives, social support, and treatment adherence within a
Initial dose: 500 mg orally once a day (this dose is generally continued for the first 1 to 2 weeks) Maintenance dose: 250 mg orally once a day (range: 125 mg to 500 mg once a day) Maximum dose: 500 mg once a day
Call your doctor for medical advice about serious side effects or adverse reactions
Disulfiram is used together with behavior modification, psychotherapy, and counseling support to help you stop drinking
Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects
CHEMICAL NAME: bis (diethylthiocarbamoyl) disulfide
As a result, acetaldehyde builds up in your body—up to five to 10 times more than what would Background: Since disulfiram’s discovery in the 1940s and its FDA approval for alcohol use disorder, other indications have been investigated
Bottle of 30 NDC 47781-607-30 - Dispense in a tight, light-resistant container as defined in the USP
Disulfiram should never be administered until the patient has abstained from alcohol for at least 12 hours
Average maintenance dosage: 250 mg daily (range: 125–500 mg daily) until patient is fully recovered socially and a basis for permanent self-control is established
Disulfiram Tablets, USP: 250 mg - White, capsule shaped tablets debossed “Σ 28” on one side and plain on the other side
monitor glucose: combo may incr
Brand name: Antabuse Drug class: drugs used in alcohol dependence Available as
Disulfiram (Antabuse) Naltrexone (ReVia) Naltrexone injection (Vivitrol) Acamprosate (Campral) Outlook
However, many people have no side effects or only have minor side effects
After the war, and more research, disulfiram was introduced as a medication for alcohol addiction, under the name Antabuse (anti-abuse)—the first of its kind
These can include: nausea; chest pain; vomiting; dizziness A disulfiram-alcohol reaction can be fatal