Torsades de pointes (TdP) is a characteristic polymorphic ventricular arrhythmia associated with delayed ventricular repolarization as evidenced on the surface electrocardiogram by QT interval prolongation
Polymorphic VT (torsades de pointes) is recognized by the inconsistent shape of QRS complexes and is often drug-related, e
Perhaps less familiar to clinicians is the fact that drugs can also trigger other arrhythmias, including bradyarrhythmias, Inotrope Digoxin 0–7 Increased vagal tone Sphingosine 1-phosphate receptor modulator Fingolimod 0
Withdrawal of any offending drugs and correction of electrolyte abnormalities are recommended in patients presenting with torsades de pointes
His past medical history included hypertension, diabetes mellitus type 2, and chronic kidney disease
Rizk J, Lazo J, Torsade de pointes is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Furosemide and have Urinary tract infection
1, 2 Medications that could delay ventricular repolarization would provoke torsade de pointes, progress to VA, and consequently lead to SCD
Its pathogenesis is associated with abnormalities of ven- tricular repolarisation which are reflected in marked lengthening of the QT interval
hypocalcaemia and digoxin or diuretic therapy
Marked QT interval prolongation and torsades de pointes occur in 3 common settings: in congenital LQTS, in a drug
155
Data sources: A MEDLINE search of the English-language literature for the period of 1980 through 1992, using the terms torsade de