Baclofen onset of action oral

com Jun 3, 2021 · Baclofen is an agonist for gamma-aminobutyric acid (GABA) B receptors on pre- and postsynaptic neurons in the central nervous system (CNS) and peripheral nervous system. 8 Baclofen has CNS depression properties and can cause sedation with tolerance, somnolence, ataxia, and respiratory and cardiovascular depression

2024-03-28
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  1. 5–1 hour in adults; peak effect in about 4 hours
  2. Oral: Initial: 2 to 2
  3. top has a very low trust score according to our algorithm
  4. Peak spasmolytic effect is seen at approximately four hours
  5. Children ≥12 years and Adolescents: Oral: 7
  6. Starting Dose – Should be started
  7. Rectal: 3 to 12 hours; IM, Oral: 3 to 4 hours
  8. 9 L/kg