Approximately 80% of fluvoxamine is bound to plasma protein, mostly albumin, over a concentration range of 20 to 2000 ng/mL
Metabolism: Fluvoxamine maleate is extensively metabolized by the liver; the main metabolic routes are oxidative demethylation and deamination
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Plasma protein binding of fluvoxamine (77%) is low compared with that of other SSRIs
Fluoxetine (Prozac) is taken by mouth, typically once Determination of fluvoxamine concentration in plasma by reversed-phase liquid chromatography
Fluvoxamine, a serotonin re-uptake inhibitor, was quantified in plasma by modifying a previously published procedure for monitoring plasma concentrations of tricyclic antidepressants
Sharyn Alfonsi reports on the unusual path fluvoxamine, a drug commonly used to treat obsessive-compulsive disorder, has had to becoming an early treatment candidate for COVID-19
The drug is affordable and widely available, which will help areas with low vaccination rates and
Screen for risk of bipolar disorder by obtaining detailed psychiatric history (e
There is a tendency for the dialyzed rate of fluvoxamine to become lower if the plasma albumin concentration is higher