Brand name: Zocor
Simvastatin helps lower cholesterol production and reduce dyslipidemia-associated complications
It works to reduce the amount of cholesterol in the blood by blocking an enzyme that is needed to make cholesterol
[4] It is used along with exercise, diet, and weight loss to decrease elevated lipid levels
" They are marketed as single-ingredient products, including Lipitor (atorvastatin), Lescol (fluvastatin), Mevacor (lovastatin), Altoprev (lovastatin extended-release), Livalo (pitavastatin), Drug class: Statins Medically reviewed by Drugs
Initially 20-40 mg once daily, dose to be taken at night, then increased if necessary up to 80 mg once daily, dose to be taken at night, adjusted at intervals of at least 4 weeks; 80 mg dose only for those with severe hypercholesterolaemia and at high risk of cardiovascular complications
Children younger than 10 years of age—Use and This class of drugs, also known as HMG CoA reductase inhibitors, works in the liver to prevent cholesterol from forming
Muscle pain, increased blood sugar levels, constipation, nausea, diarrhea, stomach pain, cramps, elevation of liver enzymes
Pravastatin and fluvastatin have a lower risk of drug interactions because they are not metabolized by cytochrome p450 3A4
Common Zocor side effects may include: headache; constipation, nausea, stomach pain; or
Pediatric patients with homozygous familial hypercholesterolemia: 20 mg/day for patients 7 to 17 years of age
Pitavastatin (Livalo® or Zypitamag®)
See full prescribing information for details regarding concomitant use of simvastatin with other drugs or grapefruit juice that increase the risk of myopathy and rhabdomyolysis
BACKGROUND: Statins are a class of prescription medicines that have been used for decades to lower low-density lipoprotein (LDL-C or "bad") cholesterol in the blood
confusion, memory problems; or
Common gemfibrozil side effects may include: stomach pain, indigestion, diarrhea; numbness or tingly feeling; dizziness, drowsiness; blurred vision; muscle or joint pain; or
This activity reviews the indications, contraindications, and mechanism of action of statins for the management of coronary heart disease and familial dyslipidemias
Statin; Drug class: Lovastatin, a compound isolated from Aspergillus terreus, was the first statin to be professionals of updates to the prescribing information concerning interactions between protease inhibitors and certain statin drugs
Call your doctor at once if you have: a light-headed feeling, like you might pass out; high blood potassium - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; low white blood cell counts - fever, mouth sores, skin sores, sore throat, cough; Drug Name Generic Name : simvastatin Brand Name: Apo-Simvastatin (CAN), Gen-Simvastatin (CAN), CO Simvastatin (CAN), Novo-Simvastatin (CAN), ratio-Simvastatin (CAN), Zocor Classification: Antihyperlipidemic, HMG-CoA reductase inhibitor Pregnancy Category X Dosage & Route Available forms : Tablets—5, 10, 20, 40, 80 mg ADULTS Initially, 20 mg PO; up to 80 mg PO daily in the evening
) Table 1, Statin Dosing and ACC/AHA Classification of Vytorin (ezetimibe / simvastatin) is a combination of two medications that work together to lower cholesterol levels
Statins (or HMG-CoA reductase inhibitors) are a class of drugs that reduce cholesterol in individuals who have dyslipidemia (abnormal fats in the blood) and thus are at risk for cardiovascular disease
Class
It is essential to recognize that these drugs are useful in combination with lifestyle modification
Data sources include Micromedex (updated 4 Feb 2024), Cerner Multum™ (updated 4 Feb 2024), ASHP (updated 12 Feb 2024) and others
HMG-CoA reductase inhibitors (statins) are lipid-lowering medications used in the primary, secondary, and tertiary prevention of coronary heart disease
Read on to learn more about Lipitor's side effects, dosage, and some frequently asked questions
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little or no urination; a seizure; low blood sugar - headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or
This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue
Call your doctor for medical advice about side effects
Pharmacotherapy
Simvastatin reduces cholesterol, Very Low-Density Lipoproteins (VLDL), and triglycerides while increasing HDL-cholesterol
Simvastatin is a methylated derivative of lovastatin that acts by competitively inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the rate-limiting step in cholesterol biosynthesis
Atorvastatin is used together with a proper diet to lower cholesterol and triglyceride (fats) levels in the blood
Simvastatin belongs to the drug class known as HMG-CoA reductase inhibitors, also called statins
Uses;
Simvastatin is an oral HMG-CoA reductase inhibitor indicated as an adjunct to diet
As a result, simvastatin (Zocor) lowers your "bad" cholesterol (called low
Simvastatin ( Zocor) is a, FDA approved prescription medication that is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise
FDA-approved statins include atorvastatin, rosuvastatin, simvastatin, pravastatin, fluvastatin, lovastatin and pitavastatin
Drug class Benefits Possible side effects; Statins Atorvastatin (Lipitor) Fluvastatin (Lescol XL) Lovastatin (Altoprev) Pitavastatin (Livalo) Pravastatin (Pravachol)
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Atorvastatin and simvastatin are the most effective at reducing LDL cholesterol levels
For dosing with the 5 mg strength, use another
Call your doctor for medical advice about side effects
Simvastatin belongs to the group of medicines called HMG-CoA reductase inhibitors, or statins
Common gemfibrozil side effects may include: stomach pain, indigestion, diarrhea; numbness or tingly feeling; dizziness, drowsiness; blurred vision; muscle or joint pain; or
This is not a complete list of side effects, and others may occur
Uses; Side effects; Warnings;
It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production of cholesterol in the liver
Initially 20–40 mg once daily, dose to be taken at night, then increased if necessary up to 80 mg once daily, dose to be taken at night, adjusted at intervals of at least 4 weeks; 80 mg dose only for those with severe hypercholesterolaemia and at high risk of cardiovascular complications
There are a variety of ways that statins differ
By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease
It blocks an enzyme (protein) in your liver from making cholesterol
[15] [16] Rosuvastatin and atorvastatin are high-intensity statins, with rosuvastatin being slightly more potent than atorvastatin
By preventing the conversion of HMG-CoA to mevalonate, statin medications decrease
lipid-lowering agents