Ondansetron, a potent antiemetic agent, is a 5-hydroxytryptamine
Thus
11, 95% CI 1
Wisniewski K, et al
9%) were exposed to oral ondansetron during the first trimester of pregnancy
Safari HR, Fassett MJ, Souter IC Prescribe ondansetron with caution to people with: QT interval prolongation — for example electrolyte disturbances and use of drugs that prolong the QT interval
From a historical cohort of 608,385 pregnancies in Denmark, women who were exposed to Moreover, an exploratory analysis showed an uptick in ear malformations among ondansetron users (2
33)
In brief, the period prevalence of exposure during pregnancy was 4
3 in 10,000) in the number of birth defect cases after ondansetron (Zofran) use in early pregnancy
Obstetric Care Provider: A health care professional who cares for a woman during pregnancy, labor, and delivery
Huybrechts KF, et al
1 A small percentage will develop hyperemesis gravidarum, which is the most common indication for hospital admission during the first part of pregnancy
Ondansetron use in early pregnancy and the risk of late pregnancy outcomes
Question Is the use of ondansetron during pregnancy associated with increased risk of cardiac malformations and oral clefts in offspring?
A significant amount of ondansetron was present in all embryonic compartments and the developmental significance of this drug exposure requires further investigation, i
ABSTRACT: Nausea and vomiting of pregnancy is a common condition that affects the health of a pregnant woman and her fetus
During the period between 1998 and 2012, 1349 women received ondansetron in early pregnancy