The ondansetron combination of the present study was the MO group
12)
Three phase III trials comparing metoclopramide with ondansetron for the prevention of acute nausea and vomiting associated with cisplatin administration have been completed to date
In the present study ondansetron was superior to metoclopramide concerning antiemetic efficacy and gave also less side-effects Dogs were administered 18 mg/m 2 cisplatin intravenously, followed 45 min later by a 15 min infusion of either placebo (saline) or antiemetic treatment with ondansetron (0
Prochlorperazine has an average rating of 3
Methods A total of 137 patients were enrolled and 80 completed the study
In a large double-blind study of antiemetic therapy conducted in Italy, 289 patients underwent 3 consecutive cycles of cisplatin chemotherapy
Ondansetron (Ond) in prophylaxis of chemotherapy-in- bined with methylprednisolone versus metoclopramide duced emesis (CE)
The results of this study suggest that ondansetron plus dexamethasone is a more effective and better tolerated anti-emetic regimen compared with metoclopramide plus dexamethasone and diphenhydramine for the prevention of acute cisplatin-induced emesis
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