If the WBC is very high, allopurinol is used to minimize complications associated with tumor lysis
If a pregnancy occurs while using the medicine, tell your doctor right away
Since hydroxyurea inhibits DNA synthesis, it can result in significant toxicity, including myelosuppression
The mean WBC count after 4 days of HU was 24 x 10 9 /L (range, 1
The European LeukemiaNet (ELN) response criteria for PV include hematocrit (HCT) < 45%
When people with sickle cell disease take hydroxyurea, they may develop a lower white blood cell or platelet count
Generic: 500 mg Tablet, Oral: Siklos: 100 mg, 1000 mg Hyperleukocytosis describes a white blood cell (WBC) count >100 x 10 9 /L (100,000/microL) in a patient with leukemia
3109/10428194
We assessed whether maintaining the platelet count below 600,000 per cubic millimeter with hydroxyurea reduces the incidence of thrombosis in patients with
3,4 An increased white blood cell (WBC) count has also been associated with poor clinical outcomes, 5,6 During PICU admission, the white blood cell (WBC) count was 77 × 10 9 /L (72% lymphocytes and 16% neutrophils), After 3 days of stable WBC count (109‐120 × 10 9 /L), hydroxyurea 20 mg/kg was administered, which was later increased to 30 mg/kg and administered as a single daily dose
Hydroxyurea also reduces the white blood count and the expression of cell adhesion molecules that contribute to vaso-occlusion and may serve as a nitric oxide donor (3, 4)
This medicine is available only with your doctor's prescription
digestive problems, including: constipation
* To learn more about this Hydroxyurea also lowers the white blood cell count (particularly the neutrophil count) and the hemoglobin which requires close monitoring with complete blood counts (CBC)
4% had a WBC count of >10x10 9 /L
Polycythemia vera is a chronic myeloproliferative neoplasm characterized by an increase in morphologically normal red cells (its hallmark), but also white cells and platelets
Canadian Brand Name
Recent personalized phase IV studies: There are 15,713 people reported to have side effects when taking Hydroxyurea
Elevation of white cell count above 11 x 109 cells/L is usually considered leukocytosis in an adult
Background
Their mean white count of 62,175/cu mm was reduced to a mean white count nadir of 26,025/cu mm (mean daily dose, 1
Avoid leukapheresis due to the risk of precipitating fatal hemorrhage
1 interaction
hydroxyurea, didanosine